Orfy-oz tab

For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only

COMPOSITION

Each film coated ORFY-OZ tablet contains:

Ofloxacin - 200mg
Ornidazole - 500mg

CATEGORY antibiotics

Ofloxacin  2nd generation fluoroquinolone
Ornidazole A nitroimidazole which is an antibacterial and antiprotozoal drug used to treat anaerobic enteric protozoa.

ORFY-OZ cover both aerobic and anaerobic infections effectively

INDICATIONS

ORFY-OZ is primarily indicated in conditions like
Polymicrobial mixed infections
Mixed diarrheas
Postoperative infections
Lower respiratory tract infections
Lung abscess/emphysema
Bronchiectasis
Upper respiratory tract infections
Chronic sinusitis
Purulent sinusitis
Peritonsillar abscess
Appendicitis
All abscesses
Biliary infections
Osteomyelitis
Wound infections
Infected decubitus ulcer
Immunocompromised patients
Infections in cancer patients
Gynecological infections
Dental infections
Diabetic foot infections.
Resistant enteric fever


DOSAGE
1 ORFY-OZ tab BD or As Prescribed by Physician.


CONTRAINDICATIONS
Hypersensitivity  It is not advocated during the first trimester of pregnancy and in those with history of tendinitis or tendon rupture following use of quinolones.lactation

ADVERSE DRUG REACTIONS

Ornidazole - Somnolence, headache, nausea, vomiting, dizziness, tremor, rigidity,
poor coordination, seizures, tiredness, vertigo, temporary loss of consciousness and signs of sensory or mixed peripheral neuropathy, taste disturbances, abnormal LFTs, skin reactions.

Ofloxacin - Nausea, vomiting, abdominal pain, diarrhoea; headache, dizziness, insomnia, hallucinations;
leucopenia and eosinophilia; vaginitis; dysgeusia; tendon damage and rupture; anorexia;
tremor; photosensitivity; hypersensitivity reactions


WARNING!

Be sure to consult your doctor before taking any medication!

"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"

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ORFY-OZ suspension

For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only

COMPOSITION

Each 5 ml ORFY - OZ suspension contains:
Ofloxacin--------- 50 mg
Ornidazole--------125 mg

CATEGORY - Anti-diarrheal

DESCRIPTION
Ofloxacin - 2nd generation fluoroquinolone, an antibacterial active against gram positive, gram negative,aerobes and atypical microorganisms

Ornidazole- 5- nitroimidazole, an antiprotozoal active against protozoa and anaerobes

MODE OF ACTION
Ofloxacin- kills bacteria by inhibiting DNA gyrase and topoisomerase 4 enzyme

Ornidazole- kills protozoa and anaerobic bacteria by producing toxic substances

INDICATIONS

ORFY-OZ suspension is indicated in-
1 Severe diarrohea
2 amoebic dysentery
3 bacillary dysentery
4 mixed dysentery

DOSAGE

Ofloxacin 7.5 mg/kg /dose BD
Ornidazole 25 mg/kg/day BD

ADVERSE EFFECTS

ORFY-OZ suspension can cause nausea, vomitings,headache, abdominal pain etc

SALIENT FEATURES

No metallic taste
Better efficacy

PACKING

ORFY-OZ suspension comes in 30 ml and 50 ml suspension

WARNING!
Be sure to consult your doctor before taking any medication!

"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"

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IGON-PLUS tab

For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only

COMPOSITION

Each uncoated tablet of  IGON-PLUS 100 contains:
cefixime  100 mg
ofloxacin 100 mg


Each film coated tablet of  IGON-PLUS contains
cefixime   200 mg
ofloxacin  200 mg

CATEGORY antibiotic
        
MODE OF ACTION

CEFIXIME
Cefixime is a 3rd generation cephalosporin.it binds with target proteins in bacterial cell wall ,interferes with synthesis of peptidoglycans making the cell wall weak and ultimately bursting and  death of the cell.

OFLOXACIN
Ofloxacin is a 2nd generation fluoroquinolone it blocks the DNA Gyrase and DNA topoisomerase 4 causing cell death.

INDICATIONS
1 Resistant typhoid fever
2 pyrexia of unknown origin

DOSAGE
Adults
1 tab of IGON-PLUS B.D. FOR 7-14 days

children
1 tab of IGON-PLUs 100 B.D.  for 7-14 days

safety in children
above 1 year

pediatric dosage
Cefixime 20mg/kg/day in 2 divided doses
( antimicrob agents chemother.2001 sep.45(9):2450-2454)

Ofloxacin 15 mg/kg/day in 2 divided doses
( ref: antimicrobial agent and chemotherapy,april 1996,p.958-961)

CONTRAINDICATIONS
pregnancy ,lactation,hypersensitivity to either cefixime or ofloxacin.

ADVERSE DRUG REACTIONS

loose stools,abdominal pain,nausea,dyspepsia,flatulence etc.

SALIENT FEATURES

Synergistic effect in eradication of salmonella typhi.
Clinical efficacy around 100%
Lesses chances of relapse
Both drugs are WHO approved for the treatment of typhoid fever.
Fever clearance time 3 days
Cefixime and ofloxacin are having excellant efficacy in UTI with 94% success rate

WARNING!

Be sure to consult your doctor before taking any medication!

"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"

Read more »