For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only
COMPOSITION
VGON syr:
Each 5 ml contains ondansetron hydrochloride IP 2 mg
VGON MD-tab:
Ondansetron ---- 4 mg
VGON inj:
Each 2 ml contains ondansetron hydrochloride IP 4 mg
CATEGORY---- anti emetic
INDICATIONS
VGON is indicated in1 Chemotherapy and radiotherapy induced emesis ,
2 Post operative nausea and vomitings ( prophylaxis )
DOSAGE
Oral dose of VGON in children -< 4 yr - 2 mg q 4 hr
4 - 11 yr - 4 mg q 4 hr
> 12 yr - 8 mg q 4 hr
IV dose for < 3 yrs old 0.15 - 0.45 mg /kg /dose
Adult dose
8 mg orally or slow iv q 4 hr
ADMINISTRATION
VGON can be taken with or without food.CONTRAINDICATIONS
Use with apomorphine (profound hypotension).SPECIAL PRECAUTIONS
VGON may cause QT prolongation; caution when used in cardiac diseases,Severe hepatic impairment.
May mask progressive ileus and/or gastric distension.
ADVERSE DRUG REACTIONS
Headache, malaise/fatigue, constipation; drowsiness, fever, dizziness, anxiety, cold sensation; pruritus, rash; diarrhoea;
gynaecological disorder, urinary retention; elevated transaminase;
local inj site reaction (pain, redness, burning); paresthesia;
hypoxia. Rarely: Anaphylaxis, angina, bronchospasm, ECG changes,
extrapyramidal symptoms, grand mal seizure, hypokalaemia,
tachycardia, vascular occlusive events.
DRUG INTERACTIONS
Rifampicin and other CYP3A4 inducers reduce levels/effects of VGON.Potentially Fatal: Concurrent use may increase the hypotensive effect of apomorphine; avoid concurrent use.
WARNING!
Be sure to consult your doctor before taking any medication!
"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"
Posted in: ANTI - EMETIC,INJECTABLES,VGON
