For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only
COMPOSITION
Each 5 ml of LXFLO suspension contains:
Milk of Magnesia IP 3.75 ml,
Liquid Paraffin IP 1.25 ml,
Sodium Picosulfate BP 3.33 mg
CATEGORY laxative
Liquid paraffin faecal softner/lubricant
Milk of magnesia osmotic laxative
Sodium picosulphate stimulant laxative
INDICATIONS
Short term treatment of constipation associated with
1 Piles
2 Anal Fissure,
3 Cardiovascular disorder
4 Hernia
5 Pre and Post operative condition
6 Endoscopy
7 Elderly and bed ridden patients
8 Bowel clearance before radioscopy.
MODE of ACTION
LXFLO suspension contains Milk of Magnesia which increases the osmotic gradient in the gut and stimulates peristalsis resulting in efficient bowel evacuation.
Sodium picosulphate in LXFLO suspension stimulates the propulsive activity of the colon, prevents absorption of water in the colonic lumen and thus promotes accumulation of water.
Liquid paraffin in LXFLO suspension lubricates bowel and softens the stools.
DOSAGE 2 tablespoonful at bedtime Should be taken with adequate water.
ADVERSE EFFECTS
Prolonged use or overdose of Sodium Picosulfate can precipitate the onset of an atonic non functional colon and hypokalemia.
Liquid Paraffin may cause aspiration pneumonia, perianal pruritus and interfere with post-operative healing following anorectal surgery. Repeated use may interfere with the absorption of essential fat-soluble substance and may cause deficiency of vitamin A, D and K.
Small amount of Magnesium gets absorbed in the circulation and may cause occasional toxicity particularly in presence of kidney damage.
CONTRAINDICATION
Hypersensitivity to any ingredient; nausea, vomiting or other symptoms of appendicitis,
acute abdominal surgery, intestinal obstruction, undiagnosed abdominal pain, pregnancy and lactation.
DRUG INTERACTIONS
Laxatives containing Magnesium salt impair absorption of Tetracycline.
Since Sodium Picosulfate increases the rate of gastrointestinal transit, it may affect the absorption of other orally administered drugs which are given concomitantly.
PACKING Bottle of 100ml.
SALIENT FEATURES
Liquid paraffin is drug of choice and more effective than lactulose in the treatment of chronic functional constipation of childhood
(ref:acta medica iranica 2007;45(3):183-188)
sodium picosulphate is an effective ,well tolerated and safe laxative in acute treatment of chronic constipation.
(ref:int.journal of clinical practice,vol 61,issue 6,page 944-950,and june 2007)
WARNING!
Be sure to consult your doctor before taking any medication!
"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"
Posted in: LAXATIVE,LIQUID PARAFFIN,LXFLO,MILK OF MAGNESIA
