DGON
Each 5 ml DGON suspension containsofloxacin------ 50 mg
ornidazole--------125 mg
CATEGORY - antidiarroeals
DESCRIPTION
Ofloxacin - 2nd generation fluoroquinolone, an antibacterial active against gram positive, gram negative,aerobes and atypical microorganismsOrnidazole- 5- nitroimidazole, an antiprotozoal active against protozoa and anaerobes
MODE OF ACTION
Ofloxacin- kills bacteria by inhibiting DNA gyrase and topoisomerase 4 enzyme
Ornidazole- kills protozoa and anaerobic bacteria by producing toxic substances
INDICATIONS
DGON suspension is indicated in-
1 Severe diarrohea
2 amoebic dysentery
3 bacillary dysentery
4 mixed dysentery
DOSAGE
Ofloxacin -----------------15 mg/kg /day bid
Ornidazole---------------- 25 mg/kg/day bid
ADVERSE EFFECTS
DGON suspension can cause nausea, vomitings,headache, abdominal pain etc
SALIENT FEATURES
No metallic taste
Better efficacy
PACKING
DGON comes in 30 ml and 50 ml suspension