Akuzole suspension

For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only

COMPOSITION

Each 5 ml of AKUZOLE suspension contains

Magaldrate            400 mg
Simethicone            20 mg

CATEGORY antacid


Magaldrate    antacid
Simethicone  antiflatulent


INDICATIONS


Hyperacidity
Peptic ulcer
Dyspepsia
Heart burn
Flatulence
Esophagitis



MODE OF ACTION


Magaldrate is the mixture of magnesium and aluminium salts

- Aluminium hydroxide works gradually and slowly therefore provides long lasting relief in hyperacidity
- Magnesium hydroxide rapidly neutralizes the acid therefore gives faster relief

Magaldrate provides rapid and sustained antacid effect with balanced effect on gut motility.

Simethicone

- It breaks down bubbles of gas in stomach and duodenum causing expulsion of gas by belching or in the form of flatus



DOSAGE

5-10 ml,4 times a day,15 minutes before meals and at bed time



ADVERSE DRUG REACTIONS


Constipation,diarrhoea,intestinal pain,numbness in oral mucosa,Drowsiness.


SPECIAL PRECAUTIONS


Pregnancy not recommended
Pediatrics not safe for children less than 6 years of age
Elderly should be given with caution in  patients with even moderate renal impairment.
Renal / hepatic impairment- should be avoided.



CONTRAINDICATIONS


Hypersensitivity,epilepsy,Hepatic impairment,GI haemorrhage,Obstruction and Perforation, Patients with Prolactin releasing pituitary hormone



SALIENT FEATURES


Magaldrate has 10 times higher acid neutralizing capacity than conventional antacids
simethicone antacid liquid combination protects gastric mucosa from the mucolyic effect of Hcl-pepsin-choline mixture.




WARNING!

Be sure to consult your doctor before taking any medication!
"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"

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AKUZOLE tab

For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only

COMPOSITION

Each tablet of AKUZOLE  contains
pantoprazole                              40 mg


CATEGORY   antacids-proton pump inhibitor (PPI), blocks 100% acid secretion.

INDICATIONS

Gastric ulcers
Deudenal ulcers
GERD
Hyperacidity

MODE OF ACTION

Pantoprazole inhibits H⁺/K⁺ ATPase pump function thereby reducing gastric acid secretion. It also has a role in the eradication of H. pylori

DOSAGE

Hyperacidity 40 mg once daily 2-4 wks


Peptic ulcer 40 mg once daily
Duration: Duodenal ulcers: 2-4 wks; Gastric ulcers: 4-8 wks.

NSAID-associated ulceration 20 mg daily.

Eradication of H. pylori infection Triple therapy: 40 mg bid combined with clarithromycin 500 mg bid and either amoxicillin 1 g bid or metronidazole 400 mg bid.

GERD 20-40 mg once daily in the morning for 4 wk, increased to 8 wk if necessary.
Maintenance: 20-40 mg daily, increased to 40 mg each morning if symptoms return


Zollinger-Ellison syndrome Initially 80 mg daily, adjusted to individual requirements. Up to 240 mg daily may be used if needed. Daily doses >80 mg should be given in 2 divided doses



ADMINISTRATION

May be taken with or without food


SPECIAL PRECAUTIONS

Long-term therapy may lead to bacterial overgrowth in the GI tract. Hepatic impairment; monitor liver function regularly (if enzymes increase, discontinue); pregnancy ( category-B ) ; not recommended in children <18 yr; long term use may lead to atrophic gastritis


CONTRAINDICATIONS

Lactation


ADVERSE DRUG REACTIONS

Diarrhoea, dizziness, pruritus, skin rashes, GI tract infections, chest pain, headache, nausea, pain, anxiety, hyperglycaemia; malaise or lassitude; myalgia; oedema; insomnia; hyperlipidaemia; flatulence, abdominal pain, constipation, eructation, dyspepsia, rectal disorder; urinary frequency, UTI; abnormalities in liver function; local site reaction; hypertonia, neck pain, weakness; bronchitis, cough, dyspnoea, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection, flu syndrome.

WARNING!

Be sure to consult your doctor before taking any medication!

"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"

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Gastrointestinal range

AKUZOLE TAB                 Pantoprazole 20mg

AKUZOLE SUSP.              Magaldrate 480 mg + Simethicone 20 mg +
                                         Domperidone 10 mg/10 ml

AKUZOLE PD SR CAP     Pantoperazole 40mg+domperidone 30 mg
                                        ( sustained release )
 
AKUZOLE RD CAP          Rabeprazole 20 mg + Domperidone 10 mg

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