For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only
COMPOSITION
Each tablet of AKUZOLE contains
pantoprazole 40 mg
CATEGORY antacids-proton pump inhibitor (PPI), blocks 100% acid secretion.
INDICATIONS
Gastric ulcers
Deudenal ulcers
GERD
Hyperacidity
MODE OF ACTION
Pantoprazole inhibits H+/K+ ATPase pump function thereby reducing gastric acid secretion. It also has a role in the eradication of H. pylori
DOSAGE
Hyperacidity 40 mg once daily 2-4 wks
Peptic ulcer 40 mg once daily
Duration: Duodenal ulcers: 2-4 wks; Gastric ulcers: 4-8 wks.
NSAID-associated ulceration 20 mg daily.
Eradication of H. pylori infection Triple therapy: 40 mg bid combined with clarithromycin 500 mg bid and either amoxicillin 1 g bid or metronidazole 400 mg bid.
GERD 20-40 mg once daily in the morning for 4 wk, increased to 8 wk if necessary.
Maintenance: 20-40 mg daily, increased to 40 mg each morning if symptoms return
Zollinger-Ellison syndrome Initially 80 mg daily, adjusted to individual requirements. Up to 240 mg daily may be used if needed. Daily doses >80 mg should be given in 2 divided doses
ADMINISTRATION
May be taken with or without food
SPECIAL PRECAUTIONS
Long-term therapy may lead to bacterial overgrowth in the GI tract. Hepatic impairment; monitor liver function regularly (if enzymes increase, discontinue); pregnancy ( category-B ) ; not recommended in children <18 yr; long term use may lead to atrophic gastritis
CONTRAINDICATIONS
Lactation
ADVERSE DRUG REACTIONS
Diarrhoea, dizziness, pruritus, skin rashes, GI tract infections, chest pain, headache, nausea, pain, anxiety, hyperglycaemia; malaise or lassitude; myalgia; oedema; insomnia; hyperlipidaemia; flatulence, abdominal pain, constipation, eructation, dyspepsia, rectal disorder; urinary frequency, UTI; abnormalities in liver function; local site reaction; hypertonia, neck pain, weakness; bronchitis, cough, dyspnoea, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection, flu syndrome.
WARNING!
Be sure to consult your doctor before taking any medication!
"The information containes herein is not intended to cover all possible uses,directions,precautions,warnings,drug interactions, allergic reactions,or adverse effects.if you have questions about the drugs you are taking, check with your doctor"
Posted in: AKUZOLE,ANTACID,PANTOPRAZOLE
